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Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors.
Stiff, Cory M; Zhong, Min; Sarver, Ronald W; Gao, Hua; Ho, Andrea M; Sweeney, Michael T; Zurenko, Gary E; Romero, Donna L.
Affiliation
  • Stiff CM; Medicinal Chemistry, Pharmacia Corporation, 301 Henrietta Street, Kalamazoo, MI 49001, USA.
Bioorg Med Chem Lett ; 17(19): 5479-82, 2007 Oct 01.
Article in En | MEDLINE | ID: mdl-17709248
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Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Carboxylic Acids / Anti-Bacterial Agents Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2007 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Search on Google
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Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Carboxylic Acids / Anti-Bacterial Agents Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2007 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido