(S)-N-{3-[1-cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: a potent, nonsteroidal, functional antagonist of the mineralocorticoid receptor.

Bell, Michael G; Gernert, Douglas L; Grese, Timothy A; Belvo, Matthew D; Borromeo, Peter S; Kelley, Sally A; Kennedy, Joseph H; Kolis, Stanley P; Lander, Peter A; Richey, Rachel; Sharp, V Scott; Stephenson, Gregory A; Williams, Jeffrey D; Yu, Hannah; Zimmerman, Karen M; Steinberg, Mitchell I; Jadhav, Prabhakar K

Bell, Michael G; Gernert, Douglas L; Grese, Timothy A; Belvo, Matthew D; Borromeo, Peter S; Kelley, Sally A; Kennedy, Joseph H; Kolis, Stanley P; Lander, Peter A; Richey, Rachel; Sharp, V Scott; Stephenson, Gregory A; Williams, Jeffrey D; Yu, Hannah; Zimmerman, Karen M; Steinberg, Mitchell I; Jadhav, Prabhakar K.

Affiliation

Bell MG; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA. bell_michael_g@Lilly.com

J Med Chem ; 50(26): 6443-5, 2007 Dec 27.

Article in En | MEDLINE | ID: mdl-18038968

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Mineralocorticoid Receptor Antagonists / Indoles / Antihypertensive Agents Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2007 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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