Perioperative myocardial injury after elective open abdominal aortic aneurysm repair predicts outcome.
Eur J Vasc Endovasc Surg
; 35(4): 413-9, 2008 Apr.
Article
in En
| MEDLINE
| ID: mdl-18063394
ABSTRACT
OBJECTIVE:
Myocardial injury, detected by rises in cardiac troponin I (TnI), is common and associated with decreased survival following open AAA surgery. We examined the relationship between perioperative myocardial injury and postoperative outcome.DESIGN:
Observational Cohort Study.METHODS:
Forty-three consecutive patients who underwent elective open AAA repair were screened for perioperative myocardial injury or infarction using serial TnI measurements (taken on days 1, 3, and 7), ECG and clinical assessment. The primary outcome was survival free of cardiac failure, or myocardial infarction (MI) at follow-up.RESULTS:
Twenty (47%) of the 43 patients had a TnI elevation. Of these, 11 (26%) patients met the criteria for MI. At a mean (+/-SD) follow-up of 1.5+/-0.8 years, 12 (28%) subjects had experienced at least one endpoint event. Survival free of cardiac failure or MI was 55% in patients who had TnI rises compared to 87% in those without (P=0.02). Logistic regression revealed that TnI elevation was an independent predictor of outcome with an odds ratio of 5.4 (95% CI 1.2-2.4, P=0.03).CONCLUSION:
Perioperative myocardial injury after elective open AAA repair predicts outcome after surgery. Routine TnI measurement should be considered in all patients, especially in those with high cardiovascular risk.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Postoperative Complications
/
Aortic Aneurysm, Abdominal
/
Heart Failure
/
Heart Injuries
/
Intraoperative Complications
/
Myocardial Infarction
Type of study:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
En
Journal:
Eur J Vasc Endovasc Surg
Journal subject:
ANGIOLOGIA
Year:
2008
Document type:
Article
Affiliation country:
Reino Unido