[A case of multiple liver metastases from rectal cancer in poor performance status successfully treated with hepatic arterial infusion chemotherapy plus CPT-11].
Gan To Kagaku Ryoho
; 34(12): 2059-61, 2007 Nov.
Article
in Ja
| MEDLINE
| ID: mdl-18219898
ABSTRACT
Hepatic arterial infusion (HAI) chemotherapy is one of the strategies for cases in poor performance status. This is a case report of multiple liver metastases from rectal cancer in poor performance status successfully treated with HAI plus CPT-11. A 59-year-old man who had rectal cancer, multiple liver metastases and para-aortic LN metastasis underwent a laparoscopic rectal anterior resection. He denied receiving postoperative chemotherapy and selected alternative therapy at another clinic. Four months later, he visited our hospital. His liver metastasis and performance status got worse, so HAI of 5-FU 1250 mg/m2 for 5-hour weekly (weekly high-dose 5-FU WHF) was started at first. After 3 courses, his status improved, so systemic chemotherapy was added. HAI (WHF 1000 mg/m2) plus CPT-11 (100 mg/m2) was effective, and liver metastases showed a significant reduction (PR) on abdominal CT. HAI plus CPT-11 was effective for a patient of the poor performance status with unresectable liver metastasis.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rectal Neoplasms
/
Camptothecin
/
Antineoplastic Combined Chemotherapy Protocols
/
Liver Neoplasms
Limits:
Humans
/
Male
/
Middle aged
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2007
Document type:
Article
Publication country:
JAPAN
/
JAPON
/
JAPÃO
/
JP