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A clinical study assessing the tolerability and biological effects of infliximab, a TNF-alpha inhibitor, in patients with advanced cancer.
Brown, E R; Charles, K A; Hoare, S A; Rye, R L; Jodrell, D I; Aird, R E; Vora, R; Prabhakar, U; Nakada, M; Corringham, R E; DeWitte, M; Sturgeon, C; Propper, D; Balkwill, F R; Smyth, J F.
Affiliation
  • Brown ER; University of Edinburgh, Cancer Research Centre, Crewe Road South, Cancer Research UK Building, Edinburgh EH4 2XR, UK.
  • Charles KA; Centre for Translational Oncology, Institute of Cancer and the CR-UK Clinical Centre, Barts and The London, Queen Mary's School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, UK.
  • Hoare SA; Centre for Translational Oncology, Institute of Cancer and the CR-UK Clinical Centre, Barts and The London, Queen Mary's School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, UK.
  • Rye RL; University of Edinburgh, Cancer Research Centre, Crewe Road South, Cancer Research UK Building, Edinburgh EH4 2XR, UK.
  • Jodrell DI; University of Edinburgh, Cancer Research Centre, Crewe Road South, Cancer Research UK Building, Edinburgh EH4 2XR, UK.
  • Aird RE; University of Edinburgh, Cancer Research Centre, Crewe Road South, Cancer Research UK Building, Edinburgh EH4 2XR, UK.
  • Vora R; Centocor R&D Inc., Malvern, PA 19355, USA.
  • Prabhakar U; Centocor R&D Inc., Malvern, PA 19355, USA.
  • Nakada M; Centocor R&D Inc., Malvern, PA 19355, USA.
  • Corringham RE; Centocor R&D Inc., Malvern, PA 19355, USA.
  • DeWitte M; Centocor R&D Inc., Malvern, PA 19355, USA.
  • Sturgeon C; Department of Clinical Biochemistry, Edinburgh Royal Infirmary, Edinburgh EH16 4SA, UK.
  • Propper D; Cancer Research UK, Medical Oncology Unit, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK.
  • Balkwill FR; Centre for Translational Oncology, Institute of Cancer and the CR-UK Clinical Centre, Barts and The London, Queen Mary's School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, UK.
  • Smyth JF; University of Edinburgh, Cancer Research Centre, Crewe Road South, Cancer Research UK Building, Edinburgh EH4 2XR, UK. Electronic address: john.smyth@ed.ac.uk.
Ann Oncol ; 19(7): 1340-1346, 2008 Jul.
Article in En | MEDLINE | ID: mdl-18325912
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Drug Hypersensitivity / Hypersensitivity, Delayed / Antibodies, Monoclonal / Neoplasms Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2008 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Drug Hypersensitivity / Hypersensitivity, Delayed / Antibodies, Monoclonal / Neoplasms Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2008 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido