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TG101348, a JAK2-selective antagonist, inhibits primary hematopoietic cells derived from myeloproliferative disorder patients with JAK2V617F, MPLW515K or JAK2 exon 12 mutations as well as mutation negative patients.
Leukemia ; 22(9): 1790-2, 2008 Sep.
Article in En | MEDLINE | ID: mdl-18354492

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Sulfonamides / Erythroid Cells / Myeloproliferative Disorders Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2008 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Sulfonamides / Erythroid Cells / Myeloproliferative Disorders Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2008 Document type: Article