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A 1,536-well [(35)S]GTPgammaS scintillation proximity binding assay for ultra-high-throughput screening of an orphan galphai-coupled GPCR.
Johnson, Eric N; Shi, Xiaoqing; Cassaday, Jason; Ferrer, Marc; Strulovici, Berta; Kunapuli, Priya.
Affiliation
  • Johnson EN; Department of Automated Biotechnology, Merck Research Laboratories, North Wales, PA 19454, USA. eric_johnson4@merck.com
Assay Drug Dev Technol ; 6(3): 327-37, 2008 Jun.
Article in En | MEDLINE | ID: mdl-18537464
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scintillation Counting / Sulfur Radioisotopes / Guanosine 5'-O-(3-Thiotriphosphate) / GTP-Binding Protein alpha Subunits, Gi-Go / Receptors, G-Protein-Coupled Type of study: Diagnostic_studies / Screening_studies Limits: Animals Language: En Journal: Assay Drug Dev Technol Journal subject: FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scintillation Counting / Sulfur Radioisotopes / Guanosine 5'-O-(3-Thiotriphosphate) / GTP-Binding Protein alpha Subunits, Gi-Go / Receptors, G-Protein-Coupled Type of study: Diagnostic_studies / Screening_studies Limits: Animals Language: En Journal: Assay Drug Dev Technol Journal subject: FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos