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A Candida albicans mannoprotein deprived of its mannan moiety is efficiently taken up and processed by human dendritic cells and induces T-cell activation without stimulating proinflammatory cytokine production.
Pietrella, Donatella; Lupo, Patrizia; Rachini, Anna; Sandini, Silvia; Ciervo, Alessandra; Perito, Stefano; Bistoni, Francesco; Vecchiarelli, Anna.
Affiliation
  • Pietrella D; Department of Experimental Medicine and Biochemical Sciences, Microbiology Section, University of Perugia, 06126 Perugia, Italy.
Infect Immun ; 76(9): 4359-67, 2008 Sep.
Article in En | MEDLINE | ID: mdl-18591233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Recombinant Proteins / Candida albicans / Membrane Glycoproteins / Lymphocyte Activation / T-Lymphocytes Limits: Humans Language: En Journal: Infect Immun Year: 2008 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Recombinant Proteins / Candida albicans / Membrane Glycoproteins / Lymphocyte Activation / T-Lymphocytes Limits: Humans Language: En Journal: Infect Immun Year: 2008 Document type: Article Affiliation country: Italia Country of publication: Estados Unidos