Monte Carlo algorithm for efficient simulation of time-resolved fluorescence in layered turbid media.
Opt Express
; 16(17): 13188-202, 2008 Aug 18.
Article
in En
| MEDLINE
| ID: mdl-18711557
ABSTRACT
We present an efficient Monte Carlo algorithm for simulation of time-resolved fluorescence in a layered turbid medium. It is based on the propagation of excitation and fluorescence photon bundles and the assumption of equal reduced scattering coefficients at the excitation and emission wavelengths. In addition to distributions of times of arrival of fluorescence photons at the detector, 3-D spatial generation probabilities were calculated. The algorithm was validated by comparison with the analytical solution of the diffusion equation for time-resolved fluorescence from a homogeneous semi-infinite turbid medium. It was applied to a two-layered model mimicking intra- and extracerebral compartments of the adult human head.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spectrometry, Fluorescence
/
Algorithms
/
Image Interpretation, Computer-Assisted
/
Imaging, Three-Dimensional
/
Luminescent Measurements
/
Microscopy, Fluorescence
/
Nephelometry and Turbidimetry
Type of study:
Health_economic_evaluation
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Opt Express
Journal subject:
OFTALMOLOGIA
Year:
2008
Document type:
Article
Affiliation country:
Polonia