Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation.

Broom, Daniel C; Matson, David J; Bradshaw, Elizabeth; Buck, Marianne E; Meade, Robin; Coombs, Susan; Matchett, Michele; Ford, Kristen K; Yu, Weifeng; Yuan, Jun; Sun, Synthia H; Ochoa, Ricardo; Krause, James E; Wustrow, David J; Cortright, Daniel N

Broom, Daniel C; Matson, David J; Bradshaw, Elizabeth; Buck, Marianne E; Meade, Robin; Coombs, Susan; Matchett, Michele; Ford, Kristen K; Yu, Weifeng; Yuan, Jun; Sun, Synthia H; Ochoa, Ricardo; Krause, James E; Wustrow, David J; Cortright, Daniel N.

Affiliation

Broom DC; Department of Pharmacology, Neurogen Corporation, Branford, Connecticut, USA. danbroom@hotmail.com

J Pharmacol Exp Ther ; 327(3): 620-33, 2008 Dec.

Article in En | MEDLINE | ID: mdl-18772321

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Benzamides / Adamantane / Anti-Inflammatory Agents, Non-Steroidal / Purinergic P2 Receptor Antagonists / Inflammation Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Pharmacol Exp Ther Year: 2008 Document type: Article Affiliation country: Estados Unidos

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