[Incidence, prevalence and risk factors for a first infectious complication on a totally implantable venous-access port]. / Incidence, prévalence et facteurs de risque de survenue d'une première complication infectieuse sur chambres à cathéter implantables.
Med Mal Infect
; 39(4): 252-8, 2009 Apr.
Article
in Fr
| MEDLINE
| ID: mdl-19108966
ABSTRACT
BACKGROUND:
Totally implantable venous-access ports (TIVAP) should present less risk of complications than central venous catheters over a long time period.AIMS:
Firstly, the study's objective was to assess the prevalence and incidence of a first infectious complication on a TIVAP and secondly, to assess the risk factors associated with this first infection.METHODS:
The authors made a longitudinal historical cohort study of patients with a TIVAP in 2003, in the Dijon University Hospital.RESULTS:
Two hundred and nineteen patients (sex-ratio 1.9) were included, with a total follow-up of 92,773 patients-days. Ninety percent of the TIVAP were used for chemotherapy, 5% for antibiotic drug administration, 2% for parenteral nutrition and 3% for other reasons (recurrent blood transfusions, etc.). Overall, 34 (16.3%) out of 209patients presented with at least one infectious complication, with an incidence rate of 0.37infection/1,000patients-days. The 5-year cumulative probability to be free of infectious complication was only 62.8%. In multivariate analysis, only underlying hematological neoplasia (by contrast with solid tumors) was significantly associated to a higher risk of infectious complication.CONCLUSIONS:
The infectious risk linked to the use of TIVAP is significant, higher in case of underlying hematological neoplasia and during the first months of use.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Catheters, Indwelling
/
Catheter-Related Infections
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Fr
Journal:
Med Mal Infect
Year:
2009
Document type:
Article
Affiliation country:
Francia