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Inhibition of iNOS and COX-2 in human whole blood ex vivo and monocyte-macrophage J774 cells by a new group of aminothiopyrimidone derivatives.
Cardile, Venera; Lombardo, Laura; Granata, Giuseppe; Perdicaro, Antonio; Balazy, Michael; Santagati, Andrea.
Affiliation
  • Cardile V; Department of Physiological Sciences, University of Catania, Catania, Italy. cardile@unict.it
Bioorg Med Chem ; 17(5): 1991-6, 2009 Mar 01.
Article in En | MEDLINE | ID: mdl-19200742

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Pyrimidinones / Sulfonamides / Enzyme Inhibitors / Cyclooxygenase 2 / Nitric Oxide Synthase Type II / Cyclooxygenase 2 Inhibitors Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: Italia

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Pyrimidinones / Sulfonamides / Enzyme Inhibitors / Cyclooxygenase 2 / Nitric Oxide Synthase Type II / Cyclooxygenase 2 Inhibitors Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: Italia