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Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta.
Hu, Baihua; Unwalla, Raymound; Collini, Michael; Quinet, Elaine; Feingold, Irene; Goos-Nilsson, Annika; Wihelmsson, Anna; Nambi, Ponnal; Wrobel, Jay.
Affiliation
  • Hu B; Chemical and Screening Science, Wyeth Research, 500 Arcola Road, Collegeville, PA 19426, USA. hub@wyeth.com
Bioorg Med Chem ; 17(10): 3519-27, 2009 May 15.
Article in En | MEDLINE | ID: mdl-19394832
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Receptors, Cytoplasmic and Nuclear / DNA-Binding Proteins / Heterocyclic Compounds, 2-Ring Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Receptors, Cytoplasmic and Nuclear / DNA-Binding Proteins / Heterocyclic Compounds, 2-Ring Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido