Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis.

Sun, Ronggai; Skeiky, Yasir A W; Izzo, Angelo; Dheenadhayalan, Veerabadran; Imam, Zakaria; Penn, Erica; Stagliano, Katherine; Haddock, Scott; Mueller, Stefanie; Fulkerson, John; Scanga, Charles; Grover, Ajay; Derrick, Steven C; Morris, Sheldon; Hone, David M; Horwitz, Marcus A; Kaufmann, Stefan H E; Sadoff, Jerald C

Sun, Ronggai; Skeiky, Yasir A W; Izzo, Angelo; Dheenadhayalan, Veerabadran; Imam, Zakaria; Penn, Erica; Stagliano, Katherine; Haddock, Scott; Mueller, Stefanie; Fulkerson, John; Scanga, Charles; Grover, Ajay; Derrick, Steven C; Morris, Sheldon; Hone, David M; Horwitz, Marcus A; Kaufmann, Stefan H E; Sadoff, Jerald C.

Affiliation

Sun R; Aeras Global TB Vaccine Foundation, 1405 Research Blvd., Rockville, MD 20850, USA.

Vaccine ; 27(33): 4412-23, 2009 Jul 16.

Article in En | MEDLINE | ID: mdl-19500523

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Tuberculosis / BCG Vaccine / Immunodominant Epitopes / Hemolysin Proteins / Antigens, Bacterial Limits: Animals Language: En Journal: Vaccine Year: 2009 Document type: Article Affiliation country: Estados Unidos Country of publication: Países Bajos

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