The use of collagen cross-linking agents to enhance dentin bond strength.
J Biomed Mater Res B Appl Biomater
; 91(1): 419-24, 2009 Oct.
Article
in En
| MEDLINE
| ID: mdl-19507140
ABSTRACT
UNLABELLED Type I collagen is a major component of the hybrid layer, and improvement of its mechanical properties may be advantageous during bonding procedures. OBJECTIVE:
To investigate the effect of three different cross-linking agents (Glutaraldehyde [GD], Grape seed extract [GSE], and Genipin [GE]) on the tensile bond strength (TBS) of resin-dentin bonds. MATERIALS ANDMETHODS:
Sixty-four sound human molars were collected and their occlusal surfaces were ground flat to expose dentin. Dentin surfaces were etched using a phosphoric acid and then teeth were randomly divided according to the dentin treatment Control group (no treatment), 5% GD, 6.5% GSE, or 0.5% GE. Teeth were restored either with One Step Plus or Adper Single Bond Plus adhesive systems and resin composite. After 24 h, teeth were sectioned to produce a cross-sectional surface area of 1.0 mm(2) and tested for tensile bond strength. Data were statistically analyzed using ANOVA and Fisher's PLSD tests (p < 0.05). There was a statistically significant interaction between factors (treatment and adhesive p < 0.001). Treatment affected TBS (p < 0.0001), while no differences were observed between the adhesive systems (p = 0.6961).CONCLUSION:
Chemical modification to the dentin matrix promoted by GD and GSE, but not GE, resulted in increased bond strength. The application of selective collagen cross-linkers during adhesive restorative procedures may be a new approach to improve dentin bond strength properties.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dental Bonding
/
Dentin-Bonding Agents
/
Cross-Linking Reagents
/
Collagen Type I
/
Dentin
Type of study:
Clinical_trials
/
Evaluation_studies
Limits:
Humans
Language:
En
Journal:
J Biomed Mater Res B Appl Biomater
Journal subject:
ENGENHARIA BIOMEDICA
Year:
2009
Document type:
Article
Affiliation country:
Estados Unidos