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Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells.
Tsang, Chi Man; Lau, Echo Ping Woi; Di, Kaijun; Cheung, Pak Yan; Hau, Pok Man; Ching, Yick Pang; Wong, Yong Chuan; Cheung, Annie Lai Man; Wan, Thomas S K; Tong, Yao; Tsao, Sai Wah; Feng, Yibin.
Affiliation
  • Tsang CM; Department of Anatomy, The University of Hong Kong, Pokfulam, Hong Kong, SAR, PR China.
Int J Mol Med ; 24(1): 131-8, 2009 Jul.
Article in En | MEDLINE | ID: mdl-19513545
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Collection: 01-internacional Database: MEDLINE Main subject: Berberine / Cell Movement / G2 Phase / Apoptosis / Rho GTP-Binding Proteins / Antineoplastic Agents Limits: Humans Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2009 Document type: Article Country of publication: Grecia
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Collection: 01-internacional Database: MEDLINE Main subject: Berberine / Cell Movement / G2 Phase / Apoptosis / Rho GTP-Binding Proteins / Antineoplastic Agents Limits: Humans Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2009 Document type: Article Country of publication: Grecia