Initiative for a new diabetes therapeutic approach in a Mediterranean country: the INDEED study.
Curr Med Res Opin
; 25(8): 1931-40, 2009 Aug.
Article
in En
| MEDLINE
| ID: mdl-19558210
ABSTRACT
AIM:
To assess the efficacy of a strategy to improve vascular risk management in patients with type 2 diabetes mellitus (T2DM).METHODS:
This was a pilot best practice implementation enhancement programme that enrolled 578 patients with T2DM. A baseline visit was followed by a concerted effort from previously trained physicians to improve adherence to lifestyle advice and optimise drug treatment for all vascular risk factors. The patients were followed-up for 6 months. The UKPDS risk engine was used to estimate vascular risk in patients without established coronary heart disease (CHD) (n = 279).RESULTS:
There was an improvement in compliance to lifestyle measures and increased prescription of evidence-based medication. In patients without established CHD there was a 37% reduction in estimated risk for CHD, 44% for fatal CHD, 10% for stroke and 25% for fatal stroke (p < or = 0.003 for all comparisons vs. baseline). There was also a substantial increase in the proportion of patients with established CHD who achieved their vascular risk factor targets.CONCLUSIONS:
This is the first study to increase the adherence to multiple interventions in patients with T2DM in both primary care and hospital settings. Education of physicians and patients, distribution of guidelines/brochures, and the completion of a one-page form, motivated both physicians and patients to achieve multiple vascular risk factor goals.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Outcome Assessment, Health Care
/
Diabetes Mellitus, Type 2
/
Diabetic Angiopathies
/
Life Style
Type of study:
Etiology_studies
/
Guideline
/
Observational_studies
/
Risk_factors_studies
/
Sysrev_observational_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Curr Med Res Opin
Year:
2009
Document type:
Article
Affiliation country:
Grecia