Mechanism-based inhibition: deriving K(I) and k(inact) directly from time-dependent IC(50) values. | J Biomol Screen;14(8): 913-23, 2009 Sep. | MEDLINE

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Mechanism-based inhibition: deriving K(I) and k(inact) directly from time-dependent IC(50) values.

Krippendorff, Ben-Fillippo; Neuhaus, Roland; Lienau, Philip; Reichel, Andreas; Huisinga, Wilhelm.

Affiliation

Krippendorff BF; Hamilton Institute, National University of Ireland Maynooth, Co. Kildare, Ireland.

J Biomol Screen ; 14(8): 913-23, 2009 Sep.

Article in En | MEDLINE | ID: mdl-19675314

Subject(s)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inhibitory Concentration 50 / Drug Antagonism / Enzyme Activation / Enzyme Inhibitors Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2009 Document type: Article Affiliation country: Irlanda

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inhibitory Concentration 50 / Drug Antagonism / Enzyme Activation / Enzyme Inhibitors Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biomol Screen Journal subject: BIOLOGIA MOLECULAR Year: 2009 Document type: Article Affiliation country: Irlanda