Pap smears for men: a vision of the future?
Ir J Med Sci
; 179(3): 459-62, 2010 Sep.
Article
in En
| MEDLINE
| ID: mdl-19763675
ABSTRACT
BACKGROUND:
Anal intraepithelial neoplasia (AIN) rarely receives as much publicity as its neighbouring orifice, the cervix. As in the cervix, intraepithelial neoplasias are precursors to cancer in the anal canal. AIN and cervical interstitial neoplasia (CIN) undergo dysplasia as a consequence of human papillomavirus (HPV) infection. Since the advent of screening with the Pap smear in CIN, cervical cancer has plummeted to a fifth of its initial incidence. Anal cancer, however, has been rising, with a predilection for human immunodeficiency virus-infected men. HPV causes a squamous epithelial dysplasia and converts healthy tissue into AINs of increasing severity until anal cancer manifests. CLINICAL CASE This article describes a clinical case of anogenital HPV infection refractory to medical and surgical therapy. It also describes an effective surgical excision technique associated with a good cosmetic outcome.CONCLUSIONS:
The paper concludes by briefly discussing the implications of a national screening programme against AIN in the future.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anus Neoplasms
/
Carcinoma in Situ
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Ir J Med Sci
Year:
2010
Document type:
Article
Affiliation country:
Irlanda