Adenovirus DNA positivity in nasopharyngeal aspirate preceding hematopoietic stem cell transplantation: a very strong risk factor for adenovirus DNAemia in pediatric patients.
Clin Infect Dis
; 49(10): 1536-9, 2009 Nov 15.
Article
in En
| MEDLINE
| ID: mdl-19845474
ABSTRACT
Human adenovirus (HAdV)-positive nasopharyngeal aspirate preceding hematopoietic stem cell transplantation was prospectively analyzed in 62 patients. By multivariate Cox proportional hazard models, HAdV-positive nasopharyngeal aspirate was the only predictor for HAdV DNAemia after hematopoietic stem cell transplantation (P < .001). HAdV DNAemia was a predictor for alloreactive disease. Early detection and intervention might help to prevent HAdV disease after hematopoietic stem cell transplantation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Viremia
/
Carrier State
/
Adenoviruses, Human
/
Nasopharynx
/
Adenoviridae Infections
/
Hematopoietic Stem Cell Transplantation
Type of study:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Language:
En
Journal:
Clin Infect Dis
Journal subject:
DOENCAS TRANSMISSIVEIS
Year:
2009
Document type:
Article
Affiliation country:
Países Bajos