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Different modes of inhibitor binding to prolyl hydroxylase by combined use of X-ray crystallography and NMR spectroscopy of paramagnetic complexes.
Poppe, Leszek; Tegley, Christopher M; Li, Vivian; Lewis, Jeffrey; Zondlo, James; Yang, Evelyn; Kurzeja, Robert J M; Syed, Rashid.
Affiliation
  • Poppe L; Department of Molecular Structure, Amgen, Inc., Thousand Oaks, California 91320, USA. lpoppe@amgen.com
J Am Chem Soc ; 131(46): 16654-5, 2009 Nov 25.
Article in En | MEDLINE | ID: mdl-19886658
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Procollagen-Proline Dioxygenase / Enzyme Inhibitors / Naphthyridines Limits: Humans Language: En Journal: J Am Chem Soc Year: 2009 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Procollagen-Proline Dioxygenase / Enzyme Inhibitors / Naphthyridines Limits: Humans Language: En Journal: J Am Chem Soc Year: 2009 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos