Plumisclerin A, a diterpene with a new skeleton from the soft coral Plumigorgia terminosclera.
Org Lett
; 12(5): 912-4, 2010 Mar 05.
Article
in En
| MEDLINE
| ID: mdl-20108913
ABSTRACT
A novel compound, named plumisclerin A (1), was isolated from samples of the soft coral Plumigorgia terminosclera collected at Mayotte Island. The compound possesses the novel plumisclerane carbon skeleton, including a tricyclo[4,3,1,0(1,5)]decane ring. Its structure and relative stereochemistry were elucidated by extensive spectroscopic analysis, including HREIMS, COSY, HSQC, HMBC, TOCSY, and NOESY experiments. In addition, the novel compound displayed in vitro cytotoxicity against selected cancer cell lines.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anthozoa
/
Diterpenes
Limits:
Animals
/
Humans
Language:
En
Journal:
Org Lett
Journal subject:
BIOQUIMICA
Year:
2010
Document type:
Article
Affiliation country:
España