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A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications.
Sheng, Zhi; Li, Li; Zhu, Lihua J; Smith, Thomas W; Demers, Andrea; Ross, Alonzo H; Moser, Richard P; Green, Michael R.
Affiliation
  • Sheng Z; Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Nat Med ; 16(6): 671-7, 2010 Jun.
Article in En | MEDLINE | ID: mdl-20495567
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Cyclic AMP Response Element-Binding Protein / Proto-Oncogene Proteins c-bcl-2 / Gene Expression Profiling / Activating Transcription Factors / Glioma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2010 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Cyclic AMP Response Element-Binding Protein / Proto-Oncogene Proteins c-bcl-2 / Gene Expression Profiling / Activating Transcription Factors / Glioma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2010 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos