Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.

Natoli, Thomas A; Smith, Laurie A; Rogers, Kelly A; Wang, Bing; Komarnitsky, Svetlana; Budman, Yeva; Belenky, Alexei; Bukanov, Nikolay O; Dackowski, William R; Husson, Hervé; Russo, Ryan J; Shayman, James A; Ledbetter, Steven R; Leonard, John P; Ibraghimov-Beskrovnaya, Oxana

Natoli, Thomas A; Smith, Laurie A; Rogers, Kelly A; Wang, Bing; Komarnitsky, Svetlana; Budman, Yeva; Belenky, Alexei; Bukanov, Nikolay O; Dackowski, William R; Husson, Hervé; Russo, Ryan J; Shayman, James A; Ledbetter, Steven R; Leonard, John P; Ibraghimov-Beskrovnaya, Oxana.

Affiliation

Natoli TA; Department of Cell Biology, Genzyme Corporation, Framingham, Massachusetts, USA.

Nat Med ; 16(7): 788-92, 2010 Jul.

Article in En | MEDLINE | ID: mdl-20562878

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Dioxanes / Glucosylceramides / Polycystic Kidney Diseases Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2010 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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