Effect of cimetidine on wedged hepatic venous pressure in cirrhotic patients.
Chin Med J (Engl)
; 104(3): 186-90, 1991 Mar.
Article
in En
| MEDLINE
| ID: mdl-2065526
ABSTRACT
According to our supposition that "humoral mechanism" plays an important role in the pathogenesis of portal hypertension due to cirrhosis, antagonists to some of humoral substances would lower the portal pressure in cirrhotic patients. Wedged hepatic venous pressure (WHVP) was used as an indicator for changes of portal pressure. Cimetidine was given intravenously to 8 cirrhotic patients, in whom an average lowering of 0.72 kPa (7.3 cm H2O) of WHVP was observed subsequently. This change was of clinical significance as compared with the previous results of splenorenal shunting operations.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cimetidine
/
Hepatic Veins
/
Liver Cirrhosis
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Chin Med J (Engl)
Year:
1991
Document type:
Article