Correlation of clinical and MRI staging in cervical carcinoma treated with radiation therapy: a single-center experience.
Diagn Interv Radiol
; 17(1): 44-51, 2011 Mar.
Article
in En
| MEDLINE
| ID: mdl-20683815
ABSTRACT
PURPOSE:
To correlate clinical and MRI findings in patients with cervical carcinoma treated with radiation therapy (RT). MATERIALS ANDMETHODS:
Forty-two patients with pretreatment IB-IVA cervical carcinoma were included in this retrospective study. Pre- and post-treatment MRI findings of the patients were reevaluated and compared with clinical staging. Six-month, one-year, and two-year follow-up imaging by MR was performed for 36, 20, and 7 patients, respectively. The correlation between clinical and MRI findings was assessed by a Spearman's rho (rank correlation) test. Univariate analyses were performed to identify the prognostic significance of the tumor volume and lymph node status.RESULTS:
Pre-treatment correlations between MRI and clinical findings for diagnoses without parametrial invasion, with parametrial invasion, and with pelvic sidewall invasion were 71.0%, 64.7%, and 15.8%, respectively. According to the Spearman's rho (rank correlation) test, the parametrial invasion correlation was poor (r = 0.410, P < 0.01). The correlation of clinical and MRI findings at 6 months was 88.9% (r = 0.674, P < 0.0001).CONCLUSION:
In advanced cervical cancer, the correlation of clinical and MRI staging prior to neoadjuvant RT was low despite a high correspondence in the assessment of local response after RT.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Magnetic Resonance Imaging
/
Uterine Cervical Neoplasms
/
Lymph Nodes
/
Neoplasm Staging
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Diagn Interv Radiol
Journal subject:
DIAGNOSTICO POR IMAGEM
/
RADIOLOGIA
Year:
2011
Document type:
Article
Affiliation country:
Turquía
Publication country:
TR
/
TURKEY
/
TURQUIA