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GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo.
Behm, D J; Aiyar, N V; Olzinski, A R; McAtee, J J; Hilfiker, M A; Dodson, J W; Dowdell, S E; Wang, G Z; Goodman, K B; Sehon, C A; Harpel, M R; Willette, R N; Neeb, M J; Leach, C A; Douglas, S A.
Affiliation
  • Behm DJ; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, King of Prussia, PA, USA. david.j.behm@gsk.com
Br J Pharmacol ; 161(1): 207-28, 2010 Sep.
Article in En | MEDLINE | ID: mdl-20718751
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urotensins / Benzamides / Receptors, G-Protein-Coupled / Benzoxazines Limits: Animals / Humans / Male Language: En Journal: Br J Pharmacol Year: 2010 Document type: Article Affiliation country: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urotensins / Benzamides / Receptors, G-Protein-Coupled / Benzoxazines Limits: Animals / Humans / Male Language: En Journal: Br J Pharmacol Year: 2010 Document type: Article Affiliation country: Estados Unidos