A heterologous MF59-adjuvanted H5N1 prepandemic influenza booster vaccine induces a robust, cross-reactive immune response in adults and the elderly.
Clin Vaccine Immunol
; 17(11): 1817-9, 2010 Nov.
Article
in En
| MEDLINE
| ID: mdl-20810680
ABSTRACT
Immunogenicity and safety of a booster dose of an MF59-adjuvanted H5N1 vaccine containing 7.5 µg A/turkey/Turkey/1/2005-like (clade 2.2) H5N1 hemagglutinin, given approximately 18 months after primary vaccination with a heterologous strain, were evaluated. The booster vaccine was well tolerated and induced a robust, cross-reactive immune response.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polysorbates
/
Squalene
/
Influenza Vaccines
/
Adjuvants, Immunologic
/
Immunization, Secondary
/
Cross Reactions
/
Influenza A Virus, H5N1 Subtype
/
Antibodies, Viral
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Vaccine Immunol
Journal subject:
ALERGIA E IMUNOLOGIA
/
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Year:
2010
Document type:
Article
Affiliation country:
Italia