SCH 2047069, a novel oral kinesin spindle protein inhibitor, shows single-agent antitumor activity and enhances the efficacy of chemotherapeutics.

Basso, Andrea D; Liu, Ming; Dai, Chaoyang; Gray, Kimberly; Nale, Lissette; Tevar, Seema; Lee, Suining; Liang, Lianzhu; Ponery, Abdul; Yaremko, Bohdan; Smith, Elizabeth; Tang, Huadong; Sheth, Payal R; Siddiqui, M Arshad; Hicklin, Daniel J; Kirschmeier, Paul

Basso, Andrea D; Liu, Ming; Dai, Chaoyang; Gray, Kimberly; Nale, Lissette; Tevar, Seema; Lee, Suining; Liang, Lianzhu; Ponery, Abdul; Yaremko, Bohdan; Smith, Elizabeth; Tang, Huadong; Sheth, Payal R; Siddiqui, M Arshad; Hicklin, Daniel J; Kirschmeier, Paul.

Affiliation

Basso AD; Department of Oncology, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07093, USA. andrea.basso@merck.com

Mol Cancer Ther ; 9(11): 2993-3002, 2010 Nov.

Article in En | MEDLINE | ID: mdl-20978164

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiadiazoles / Benzopyrans / Kinesins / Neoplasms / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2010 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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