Treatment of hyperstimulation during in-vitro fertilization.
Hum Reprod
; 5(1): 36-9, 1990 Jan.
Article
in En
| MEDLINE
| ID: mdl-2108982
ABSTRACT
In 33 patients treated with a combination of an LHRH agonist (LHRH-A) and gonadotrophin in a long protocol, a biological hyperstimulation occurred (E2 greater than 2500 pg/ml on the day of HCG administration and 4722 +/- 1190 pg/ml the day after, with greater than 10 follicles greater than 12 mm on each ovary). The replacement of fresh embryos were deferred and LHRH-A was continued, and an endometrial biopsy was performed on the theoretical day of replacement (2 days after oocyte recovery). With this technique, we obtained a mean number of 17.9 +/- 7 oocytes, a fertilization rate of 49% and a replacement rate of 87% in a deferred cycles. The overall pregnancy rate of frozen-thawed embryos was 27% in the seven spontaneous cycles, 12 induced cycles and 10 artificial cycles. Only one severe hyperstimulation occurred and this case emphasizes that caution remains necessary even with this technique.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ovulation
/
Ovulation Induction
/
Superovulation
/
Fertilization in Vitro
Limits:
Female
/
Humans
Language:
En
Journal:
Hum Reprod
Journal subject:
MEDICINA REPRODUTIVA
Year:
1990
Document type:
Article
Affiliation country:
Francia