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Monocyclic ß-lactams are selective, mechanism-based inhibitors of rhomboid intramembrane proteases.
Pierrat, Olivier A; Strisovsky, Kvido; Christova, Yonka; Large, Jonathan; Ansell, Keith; Bouloc, Nathalie; Smiljanic, Ela; Freeman, Matthew.
Affiliation
  • Pierrat OA; MRC Laboratory of Molecular Biology, Cambridge, U.K.
ACS Chem Biol ; 6(4): 325-35, 2011 Apr 15.
Article in En | MEDLINE | ID: mdl-21175222
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Monobactams / Serine Proteinase Inhibitors / Serine Proteases / High-Throughput Screening Assays / Membrane Proteins Limits: Animals Language: En Journal: ACS Chem Biol Year: 2011 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Monobactams / Serine Proteinase Inhibitors / Serine Proteases / High-Throughput Screening Assays / Membrane Proteins Limits: Animals Language: En Journal: ACS Chem Biol Year: 2011 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos