Tau phosphorylation both in vitro and in cells.
Methods Mol Med
; 32: 375-93, 2000.
Article
in En
| MEDLINE
| ID: mdl-21318533
Tau was originally isolated from brain microtubules and shown to be a microtubule-associated protein (MAP) that promoted tubulin polymerization (1). It is largely confined to axons, where it is the major MAP. It promotes microtubule nucleation, elongation, and bundling, and stabilizes microtubules by inhibiting depolymerization.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Methods Mol Med
Journal subject:
BIOLOGIA MOLECULAR
Year:
2000
Document type:
Article
Country of publication:
Estados Unidos