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Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1.
Danson, S J; Johnson, P; Ward, T H; Dawson, M; Denneny, O; Dickinson, G; Aarons, L; Watson, A; Jowle, D; Cummings, J; Robson, L; Halbert, G; Dive, C; Ranson, M.
Affiliation
  • Danson SJ; Department of Medical Oncology, University of Manchester, Christie Hospital NHS Foundation Trust, Manchester; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research. Electronic address: s.danson@sheffield.ac.uk.
  • Johnson P; Cancer Research UK Clinical Centre, Southampton General Hospital, Southampton.
  • Ward TH; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research.
  • Dawson M; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research.
  • Denneny O; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research.
  • Dickinson G; School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester.
  • Aarons L; School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester.
  • Watson A; Cancer Research UK Clinical Centre, Southampton General Hospital, Southampton.
  • Jowle D; Department of Medical Oncology, University of Manchester, Christie Hospital NHS Foundation Trust, Manchester.
  • Cummings J; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research.
  • Robson L; Cancer Research UK Drug Development Office, Cancer Research UK, London.
  • Halbert G; Cancer Research UK Formulation Unit, University of Strathclyde, Glasgow, UK.
  • Dive C; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research.
  • Ranson M; Department of Medical Oncology, University of Manchester, Christie Hospital NHS Foundation Trust, Manchester; Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research.
Ann Oncol ; 22(7): 1653-1660, 2011 Jul.
Article in En | MEDLINE | ID: mdl-21378203
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aziridines / Benzoquinones / NAD(P)H Dehydrogenase (Quinone) / Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2011 Document type: Article Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aziridines / Benzoquinones / NAD(P)H Dehydrogenase (Quinone) / Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2011 Document type: Article Country of publication: Reino Unido