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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.
Buchanan, John L; Newcomb, John R; Carney, David P; Chaffee, Stuart C; Chai, Lilly; Cupples, Rod; Epstein, Linda F; Gallant, Paul; Gu, Yan; Harmange, Jean-Christophe; Hodge, Kathy; Houk, Brett E; Huang, Xin; Jona, Janan; Joseph, Smriti; Jun, H Toni; Kumar, Rakesh; Li, Chun; Lu, John; Menges, Tom; Morrison, Michael J; Novak, Perry M; van der Plas, Simon; Radinsky, Robert; Rose, Paul E; Sawant, Satin; Sun, Ji-Rong; Surapaneni, Sekhar; Turci, Susan M; Xu, Keyang; Yanez, Evelyn; Zhao, Huilin; Zhu, Xiaotian.
Affiliation
  • Buchanan JL; Department of Medicinal Chemistry, Amgen Inc., 360 Binney Street, Cambridge, MA 02142, USA. john.buchanan@amgen.com
Bioorg Med Chem Lett ; 21(8): 2394-9, 2011 Apr 15.
Article in En | MEDLINE | ID: mdl-21414779
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Quinolines / Receptor, IGF Type 1 / Protein Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Quinolines / Receptor, IGF Type 1 / Protein Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido