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Oversulfated chondroitin sulfate and OSCS-contaminated heparin cause dose- and route-dependent hemodynamic effects in the rat.
Corbier, Alain; Le Berre, Nathalie; Rampe, David; Meng, Harry; Lorenz, Martin; Vicat, Pascale; Potdevin, Sophie; Doubovetzky, Michel.
Affiliation
  • Corbier A; Department of Disposition, Safety and Animal Research, Sanofi-aventis R&D, Vitry-sur-Seine 94400 France.
Toxicol Sci ; 121(2): 417-27, 2011 Jun.
Article in En | MEDLINE | ID: mdl-21436127
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin / Drug Contamination / Chondroitin Sulfates / Kallikrein-Kinin System Limits: Animals / Female / Humans / Male Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2011 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin / Drug Contamination / Chondroitin Sulfates / Kallikrein-Kinin System Limits: Animals / Female / Humans / Male Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2011 Document type: Article