Analytical method for the simultaneous determination of polyfunctional amines used as monomers in the manufacture of food packaging materials.
J Chromatogr A
; 1218(40): 7105-9, 2011 Oct 07.
Article
in En
| MEDLINE
| ID: mdl-21868021
ABSTRACT
This paper describes the development of a multi-analyte method for the determination of polyfunctional amines commonly used as monomers in the manufacture of food contact materials. Amines were analyzed by high-performance-liquid chromatography with diode-array detection (HPLC-DAD) after derivatization with dansyl chloride. The chromatographic analysis and the derivatization conditions were optimized. The proposed method was validated in terms of linearity, limits of detection and repeatabilities. The method showed an excellent sensitivity (LOD≤0.05 µg/mL) and appropriate repeatabilites (RSD (n=7)≤5%)). LC-MS/MS was used as a confirmatory technique. The stability of the amines in five food simulants (distilled water, 3% acetic acid, 10% ethanol, 50% ethanol and olive oil) under the most common testing conditions (10 days at 40 °C) was also studied. Results showed that amines had an acceptable stability in aqueous simulants but in the olive oil a loss of 100% was observed for all analytes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chromatography, High Pressure Liquid
/
Food Packaging
/
Tandem Mass Spectrometry
/
Amines
Type of study:
Diagnostic_studies
/
Prognostic_studies
Language:
En
Journal:
J Chromatogr A
Year:
2011
Document type:
Article
Affiliation country:
España