Neuroendocrine carcinoma of the apocrine glands of the anal sac in a dog.
J Vet Diagn Invest
; 23(4): 852-6, 2011 Jul.
Article
in En
| MEDLINE
| ID: mdl-21908338
ABSTRACT
A perianal subcutaneous tumor involving the anal sac developed in an 8-year-old male mixed Labrador Retriever dog. Histologically, this tumor showed typical features of the solid-type carcinoma of the apocrine glands of the anal sac. However, neoplastic cells were immunoreactive for cytokeratin 8, chromogranin A, vasoactive intestinal peptide, neuron-specific enolase, and synaptophysin, and negative for S-100 protein, α-smooth muscle actin, vimentin, glucagon, insulin, somatostatin, carcinoembryonic antigen, serotonin, and parathyroid hormone-related protein. Considering the distribution of chromogranin A-positive cells within the anal sac apocrine glands, this tumor was diagnosed as neuroendocrine carcinoma originating from the apocrine glands of the anal sac.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Apocrine Glands
/
Soft Tissue Neoplasms
/
Carcinoma, Neuroendocrine
/
Dog Diseases
/
Anal Sacs
Type of study:
Diagnostic_studies
Limits:
Animals
Language:
En
Journal:
J Vet Diagn Invest
Journal subject:
MEDICINA VETERINARIA
Year:
2011
Document type:
Article
Affiliation country:
Japón