TNF-&#945; and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.

Wang, Jianru; Markova, Dessislava; Anderson, D Greg; Zheng, Zhaomin; Shapiro, Irving M; Risbud, Makarand V

TNF-α and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.

Wang, Jianru; Markova, Dessislava; Anderson, D Greg; Zheng, Zhaomin; Shapiro, Irving M; Risbud, Makarand V.

Affiliation

Wang J; Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

J Biol Chem ; 286(46): 39738-49, 2011 Nov 18.

Article in En | MEDLINE | ID: mdl-21949132

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Procollagen N-Endopeptidase / Tumor Necrosis Factor-alpha / ADAM Proteins / Aggrecans / Interleukin-1beta / Syndecan-4 / Intervertebral Disc Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Document type: Article Affiliation country: Estados Unidos

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