Synthesis of 2H-indazoles by the [3 + 2] dipolar cycloaddition of sydnones with arynes.
J Org Chem
; 76(21): 8840-51, 2011 Nov 04.
Article
in En
| MEDLINE
| ID: mdl-21970468
ABSTRACT
A rapid and efficient synthesis of 2H-indazoles has been developed using a [3 + 2] dipolar cycloaddition of sydnones and arynes. A series of 2H-indazoles have been prepared in good to excellent yields using this protocol, and subsequent Pd-catalyzed coupling reactions can be applied to the halogenated products to generate a structurally diverse library of indazoles.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sydnones
/
Indazoles
Language:
En
Journal:
J Org Chem
Year:
2011
Document type:
Article
Affiliation country:
Estados Unidos