Complete genome sequence of human adenovirus prototype 17.
J Virol
; 85(21): 11540-1, 2011 Nov.
Article
in En
| MEDLINE
| ID: mdl-21980031
ABSTRACT
As one of the first five human adenoviruses (HAdVs) to be sequenced, type 17 was important as a reference tool for comparative genomics of recently isolated HAdV pathogens in species D. HAdV-D17 was the first species D adenovirus to be sequenced and was deposited in GenBank in 1999. These genome data were not of high quality, and a redetermination of the same stock virus provides corrected data; among the differences are a length of 35,139 bp versus 35,100 bp in the original, and 160 mismatches to the original genome were found. Annotation of the coding sequences reveals 39 as opposed to 8, a finding which is important for phylogenomic studies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
DNA, Viral
/
Adenoviruses, Human
/
Genome, Viral
/
Adenoviridae Infections
Limits:
Humans
Language:
En
Journal:
J Virol
Year:
2011
Document type:
Article
Affiliation country:
Estados Unidos