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Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore.
Franceschini, Lorenzo; Mikhailova, Ellina; Bayley, Hagan; Maglia, Giovanni.
Affiliation
  • Franceschini L; Department of Chemistry, University of Leuven, 3001, Heverlee, Leuven, Belgium.
Chem Commun (Camb) ; 48(10): 1520-2, 2012 Feb 01.
Article in En | MEDLINE | ID: mdl-22089628
ABSTRACT
The four DNA bases are recognized in immobilized DNA strands at high alkaline pH by nanopore current recordings. Ionic currents through the biological nanopores are also employed to measure the apparent pK(a) values of single nucleobases within the immobilised DNA strands.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Alkalies / Nanopores Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Bélgica
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Alkalies / Nanopores Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Bélgica