The role of T and B cells in atherosclerosis: potential clinical implications.
Curr Pharm Des
; 17(37): 4159-71, 2011 Dec.
Article
in En
| MEDLINE
| ID: mdl-22204376
ABSTRACT
The chronic inflammation process that characterises atherosclerosis involves both the innate and adaptive arms of the immune system. Several lines of evidence have recently highlighted pivotal roles for T and B lymphocytes - cells that belong to the adaptive immune system - in the development and progression of atherosclerosis. In this review, we summarise the current knowledge on the roles of adaptive immune responses in atherosclerosis and present our views on how a better understanding of these immune mechanisms could shape future therapies to slow down or even prevent this disease.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
B-Lymphocytes
/
T-Lymphocytes
/
Atherosclerosis
Type of study:
Etiology_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Curr Pharm Des
Journal subject:
FARMACIA
Year:
2011
Document type:
Article
Affiliation country:
Reino Unido