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Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010.
Papenburg, Jesse; Carbonneau, Julie; Hamelin, Marie-Ève; Isabel, Sandra; Bouhy, Xavier; Ohoumanne, Najwa; Déry, Pierre; Paes, Bosco A; Corbeil, Jacques; Bergeron, Michel G; De Serres, Gaston; Boivin, Guy.
Affiliation
  • Papenburg J; McGill University Health Centre, Montréal, Québec, Canada.
Emerg Infect Dis ; 18(1): 120-4, 2012 Jan.
Article in En | MEDLINE | ID: mdl-22264682
ABSTRACT
To assess molecular evolution of the respiratory syncytial virus (RSV) fusion gene, we analyzed RSV-positive specimens from 123 children in Canada who did or did not receive RSV immunoprophylaxis (palivizumab) during 2006-2010. Resistance-conferring mutations within the palivizumab binding site occurred in 8.7% of palivizumab recipients and none of the nonrecipients.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Viruses / Viral Fusion Proteins / Respiratory Syncytial Virus Infections / Evolution, Molecular Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Humans Country/Region as subject: America do norte Language: En Journal: Emerg Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2012 Document type: Article Affiliation country: Canadá
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Viruses / Viral Fusion Proteins / Respiratory Syncytial Virus Infections / Evolution, Molecular Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Humans Country/Region as subject: America do norte Language: En Journal: Emerg Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2012 Document type: Article Affiliation country: Canadá