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Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.
Li, Yanyan; Karagöz, G Elif; Seo, Young Ho; Zhang, Tao; Jiang, Yiqun; Yu, Yanke; Duarte, Afonso M S; Schwartz, Steven J; Boelens, Rolf; Carroll, Kate; Rüdiger, Stefan G D; Sun, Duxin.
Affiliation
  • Li Y; Department of Pharmaceutical Sciences, University of Michigan, MI, USA.
J Nutr Biochem ; 23(12): 1617-26, 2012 Dec.
Article in En | MEDLINE | ID: mdl-22444872
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Thiocyanates / HSP90 Heat-Shock Proteins / Chaperonins / Cell Cycle Proteins Limits: Animals / Female / Humans Language: En Journal: J Nutr Biochem Journal subject: BIOQUIMICA / CIENCIAS DA NUTRICAO Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Thiocyanates / HSP90 Heat-Shock Proteins / Chaperonins / Cell Cycle Proteins Limits: Animals / Female / Humans Language: En Journal: J Nutr Biochem Journal subject: BIOQUIMICA / CIENCIAS DA NUTRICAO Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos