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Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors.
Gregus, Ann M; Doolen, Suzanne; Dumlao, Darren S; Buczynski, Matthew W; Takasusuki, Toshifumi; Fitzsimmons, Bethany L; Hua, Xiao-Ying; Taylor, Bradley K; Dennis, Edward A; Yaksh, Tony L.
Affiliation
  • Gregus AM; Department of Anesthesiology, University of California at San Diego, La Jolla, CA 92093-0818, USA.
Proc Natl Acad Sci U S A ; 109(17): 6721-6, 2012 Apr 24.
Article in En | MEDLINE | ID: mdl-22493235
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord / Arachidonate 12-Lipoxygenase / 8,11,14-Eicosatrienoic Acid / Transient Receptor Potential Channels / TRPV Cation Channels / Hyperalgesia / Inflammation Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2012 Document type: Article Affiliation country: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord / Arachidonate 12-Lipoxygenase / 8,11,14-Eicosatrienoic Acid / Transient Receptor Potential Channels / TRPV Cation Channels / Hyperalgesia / Inflammation Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2012 Document type: Article Affiliation country: Estados Unidos