Guanacastane-type diterpenoids from Coprinus radians.
Phytochemistry
; 78: 190-6, 2012 Jun.
Article
in En
| MEDLINE
| ID: mdl-22521133
ABSTRACT
Thirteen diterpenoids, named radianspenes A-M (1-13), including three lactams radianspenes J (10), K (11) and L (12) and one dimer radianspene M (13), were isolated from fermentation products of the higher fungal strain Coprinus radians M65. All these compounds possessing guanacastane skeleton were evaluated for antitumor activity using MDA-MB-435 cell line. Radianspene C exhibited inhibitory activity with IC(50) of 0.91 µM.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Coprinus
/
Diterpenes
Language:
En
Journal:
Phytochemistry
Year:
2012
Document type:
Article