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Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors.
Bode, Christiane M; Boezio, Alessandro A; Albrecht, Brian K; Bellon, Steven F; Berry, Loren; Broome, Martin A; Choquette, Deborah; Dussault, Isabelle; Lewis, Richard T; Lin, Min-Hwa Jasmine; Rex, Karen; Whittington, Douglas A; Yang, Yajing; Harmange, Jean-Christophe.
Affiliation
  • Bode CM; Amgen Inc., 360 Binney St., Cambridge, MA 02142, USA. aboezio@amgen.com
Bioorg Med Chem Lett ; 22(12): 4089-93, 2012 Jun 15.
Article in En | MEDLINE | ID: mdl-22595176
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Quinolines / Triazoles / Proto-Oncogene Proteins c-met / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Quinolines / Triazoles / Proto-Oncogene Proteins c-met / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido