Ten-year follow-up after autologous stem cell transplantation of a patient with immunoglobulin light-chain (AL) amyloidosis with deposits in the heart, liver and gastrointestinal tract.
BMJ Case Rep
; 20112011 Aug 17.
Article
in En
| MEDLINE
| ID: mdl-22688930
ABSTRACT
The prognosis in amyloid light chain (AL)-amyloidosis and multiorgan involvement is poor, with a high-treatment-related mortality after high-dose melphalan and autologous stem cell transplantation (HDM/SCT). Some patients, however, might benefit from the therapy. We report a case of cardiac AL-amyloidosis with multiorgan involvement where the progressive cardiomyopathy was halted after successful treatment with HDM/SCT in 2001. The patient is in an excellent cardiac condition with a good quality of life, receiving treatment with angiotensinogen receptor blockers and a flexible diuretics regimen at follow-up after 10 years.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Immunoglobulin Light Chains
/
Stem Cell Transplantation
/
Gastrointestinal Diseases
/
Heart Diseases
/
Amyloidosis
/
Liver Diseases
Type of study:
Observational_studies
/
Prognostic_studies
Aspects:
Patient_preference
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
BMJ Case Rep
Year:
2011
Document type:
Article
Affiliation country:
Suecia