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Triplex-directed covalent cross-linking of a DNA nanostructure.
Rusling, David A; Nandhakumar, Iris S; Brown, Tom; Fox, Keith R.
Affiliation
  • Rusling DA; Centre for Biological Sciences, University of Southampton, Highfield, Southampton, UK. D.A.Rusling@soton.ac.uk
Chem Commun (Camb) ; 48(77): 9592-4, 2012 Oct 07.
Article in En | MEDLINE | ID: mdl-22911369
The triplex approach to DNA recognition is exploited to direct covalent inter-strand cross-links to unique locations within a pre-assembled DNA nanostructure. This approach can be used to improve the stability of DNA nanostructures and demonstrates the feasibility of directing other reactive groups to unique locations within these complexes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Cross-Linking Reagents / Nanostructures Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2012 Document type: Article Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Cross-Linking Reagents / Nanostructures Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2012 Document type: Article Country of publication: Reino Unido