Bioactive oligostilbenoids from Shorea maxwelliana King and their chemotaxonomic significance.
Nat Prod Res
; 27(17): 1589-93, 2013.
Article
in En
| MEDLINE
| ID: mdl-23035830
ABSTRACT
Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic activities. Neurotoxicity for all tested compounds did not pose any toxic effect against cultured cell (cell viability range ±100-94%). Compounds 2-5 possessed active cyctotoxic activity against HL60 cell line with IC50 values range of 2.7-78 µg mL(-1).
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stilbenes
/
Plant Bark
/
Dipterocarpaceae
Limits:
Humans
Language:
En
Journal:
Nat Prod Res
Year:
2013
Document type:
Article
Affiliation country:
Malasia
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM